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© 1972 Oxford University Press

research-article

MORE FAVOURABLE PROGNOSIS OF MOTOR NEURONE DISEASE IN OLD AGE

H. M. HODKINSON

Northwick Park Hospital Harrow, Middlesex

The prognosis of motor neurone disease as seen in a series of 13 patients over 65 years of age was unexpectedly favourable in comparison to that given in published accounts and largely based on experience in younger age-groups. The average length of survival from onset to death was 5–4 years with three patients still alive at 4, 10 and 18 years. The prognostic effects of bulbar involvement, universally reported as unfavourable, appeared to be reversed in old age, indeed the two most remarkable survivals were both in women with bulbar involvement, one dying after 19 years and the other still surviving after 18 years. High age of onset of motor neurone disease appeared to confer a relatively better prognosis.


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