Skip Navigation

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by CASALE, G.
Right arrow Articles by NICOLA, P. d.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by CASALE, G.
Right arrow Articles by NICOLA, P. d.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© 1983 Oxford University Press

research-article

CIRCADIAN RHYTHM OF IMMUNOGLOBULINS IN AGED PERSONS

G. CASALE, Assistant, G. L MARINONI, Assistant, R. d'ANGELO, Assistant and P. de NICOLA, Professor and Director

Institute of Gerontology and Geriatrics, University of Pavia Piazza Borromeo, 2, 27100 Pavia, Italy
Istituto Geriatrico Piero Redaelli Sede di Milano
Istituto Geriatrico Piaro Redaelli Sede di Milano
Institute of Gerontology and Geriatrics, University of Pavia

A circadian rhythm with a high statistical probability was detected for IgA, IgG and IgM in a group of 37 aged subjects. These rhythms have a peak (acrophase) in the early afternoon, around 13h00, with variable confidence interval, which may extend between 8h30 and 17h30. The double amplitude of rhythms is approximately 15% of the mean concentration of antibodies during the day (mesor). No statistical difference was observed in mesor, amplitude or acrophase between males and females or in association with age (below or above 75 years) or in mean concentration of immunoglobulins (inside or outside the adult standard reference value at 8h00).


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.