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© 1987 Oxford University Press

research-article

A SERO-EPIDEMIOLOGICAL STUDY OF CONVENTIONAL INFECTIOUS AGENTS IN ALZHEIMER'S DISEASE

E. B. RENVOIZE, Formerty Consultant Psychiatrist*,1, L O. AWAD, Senior Registrar in Psychiatry2 and M. H. HAMBLING, Consultant Virologist3

1Bootham Park Hospital York, YO3 7BY
2St James's University Hospital Beckatt Street, Leeds LS9 7TF
3Public Health Laboratory Bridle Path, York Road, Leeds LS15 7TR

*Dr E. B. Renvoize, Department of Community Medicine, Leeds General Infirmary, Great George Street, Leeds LS1 3EX, Yorkshire.

Serum antibody titres to Adenovirus, Chlamydia Group B, Coxiella burnettii, Cytomegalovirus, Herpes simplex virus, Influenza A, Influenza B, Measles and Mycoplasma pneumoniae were measured in 33 patients with a clinical diagnosis of Alzheimer's disease, and in 28 non-demented controls suffering from functional psychiatric disorders. No statistically significant differences were found between the patients and controls, and it is concluded that these agents play no role in the aetiology of Alzheimer's disease.


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