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© 1988 Oxford University Press

research-article

BONE MASS AND DEMENTIA IN HIP FRACTURE PATIENTS FROM AREAS WITH DIFFERENT ALUMINIUM CONCENTRATIONS IN WATER SUPPLIES

D. J. WOOD, Senior Registrar in Orthopaedic Surgery, C. COOPER, Epidemiologist, J. STEVENS, Professor of Orthopaedic Surgery and J. EDWARDSON, Director, and Professor of Neuroendocrinology

Department of Orthopaedic Surgery, Leicestar Royal Infirmary Leicestar
The MRC Environmental Epidemiology Unit, Southampton General Hospital Southampton
Royal Victoria Infirmary Newcastle upon Tyne
The MRC Neuroendoerinology Unit, Newcastle General Hospital Newcastle upon Tyne

Address correspondence to Mr D. Wood, Department of Orthopaedic Surgery, Leicester Royal Infirmary, Leicester.

The relationship between bone mass and dementia in elderly hip fracture patients from areas with different aluminium concentrations in water supplies has been investigated, to determine whether a high concentration of aluminium in the drinking water and the negative calcium balance of age-related osteoporosis together predispose to senile dementia.

Mental test scores were recorded on admission to hospital, and Singh indices of radiographs taken at that time assessed blind by a single trained observer.

No significant difference in either mental test score (X=1.253, df=2, P=0.53) or Singh index (X=1.039, df=5, P=0.96) was found between patients resident in high versus low water aluminium areas. No correlation was detectable between mental test score and Singh index (X=0.95, df=1, P=0.33).

accepted in revised form February 6, 1988.


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