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© 1989 Oxford University Press

research-article

The Implementation of a Multicentred Randomized Controlled Trial in the Evaluation of the Experimental National Health Service Nursing Homes

JOHN BOND, BARBARA A. GREGSON, ANN ATKINSON and DAVID J. NEWELL

Health Care Research Unit, 21 Claremont Place, The University Newcastle upon Tyne NE2 4AA*
Policy Services Unit, Newcastle City Council, Civic Centre Newcastle upon Tyne NE1 8QN
Emeritus Professor of Medical Statistics, University of Newcastle upon Tyne

*Address for correspondence

This paper reviews the implementation of a pragmatic multicentred randomized controlled trial in the evaluation of three experimental nursing homes. The organization of services for the care of elderly people varied between the three centres, and each used different criteria for selecting subjects for the trial and different methods of seeking informed consent. Data presented show that in each centre two truly randomized samples have been selected. However, differences between centres, in the characteristics of selected subjects, reflect the implementation of the trials in each of the centres. These findings emphasize the importance of good collaboration between health professionals providing the service, an independent research team, and the establishment of rigorous criteria for inclusion and exclusion of subjects at the outset.

accepted in revised form September 17, 1988.


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