Skip Navigation

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (26)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by O'ROURKE, N. P.
Right arrow Articles by CLAYTON, B. E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by O'ROURKE, N. P.
Right arrow Articles by CLAYTON, B. E.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© 1990 Oxford University Press

research-article

Thiamine Status of Healthy and Institutionalized Elderly Subjects: Analysis of Dietary Intake and Biochemical Indices

NICHOLAS P. O'ROURKE, VALDA W. BUNKER*, ANITA J. THOMAS, PAUL M. FINGLAS, ANGELA L. BAILEY and BARBARA E. CLAYTON

University Department of Geriatric Medicine, Faculty of Medicine, Southampton General Hospital Tremona Road, Southampton, Hants SO9 4XY
Nutrition and Food Quality Department, AFRC Institute of Food Research, Norwich Laboratory Colney Lane, Norwich NR4 7UA

*Address correspondence to Dr V. Bunker

Thiamine status was assessed in healthy young and elderly subjects and institutionalized elderly patients by measuring dietary intake, erythrocyte levels of thiamine and the activity of the thiamine-dependent enzyme, erythrocyte transketolase, with and without the addition of excess thiamine pyrophosphate (the TPP effect). Healthy elderly subjects had a reduced intake of thiamine compared with the younger subjects but erythrocyte levels of thiamine and the TPP effect were comparable, suggesting adequate thiamine status. The institutionalized elderly patients had a low intake of thiamine compared with the healthy elderly as well as abnormal biochemical indices suggestive of suboptimal thiamine status Thiamine deficiency does not appear to be a problem in healthy elderly people but those in institutions are at risk of deficiency which might adversely affect their clinical state.

Received December 24, 1989;
Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 J Am Coll CardiolHome page
S. A. Hanninen, P. B. Darling, M. J. Sole, A. Barr, and M. E. Keith
The Prevalence of Thiamin Deficiency in Hospitalized Patients With Congestive Heart Failure
J. Am. Coll. Cardiol., January 17, 2006; 47(2): 354 - 361.
[Abstract] [Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.