Skip Navigation

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (39)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by BURNS, A.
Right arrow Articles by LEVY, R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by BURNS, A.
Right arrow Articles by LEVY, R.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© 1991 Oxford University Press

research-article

Neurological Signs in Alzheimer's Disease

ALISTAIR BURNS, ROBIN JACOBY and RAYMOND LEVY

Section of Old Age Psychiatry, Institute of Psychiatry De Crespigny Park, Denmark Hill, London SE5 8AF

Neurological signs were assessed in 178 patients satisfying NINCDS/ADRDA criteria for Alzheimer's disease. A snout reflex was present in 41%, extrapyramidal signs in 12%, drug-induced extrapyramidal signs in 3%, myoclonus in 5%, and a history of epileptic fits in 3%. A grasp reflex, extrapyramidal signs and symptoms were associated with severe cognitive impairment. On CT scanning, extrapyramidal signs were associated with increased 3rd ventricular size and basal ganglia calcification, a grasp reflex with frontal lobe atrophy and a history of epilepsy with left temporal lobe atrophy. Lateral ventricular size was greater in patients developing a grasp reflex during a 12 month follow-up. Extrapyramidal signs and primitive reflexes were associated with a higher mortality.

Received April 4, 1990;
Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 NeurologyHome page
N. Scarmeas, M. Albert, J. Brandt, D. Blacker, G. Hadjigeorgiou, A. Papadimitriou, B. Dubois, M. Sarazin, D. Wegesin, K. Marder, et al.
Motor signs predict poor outcomes in Alzheimer disease
Neurology, May 24, 2005; 64(10): 1696 - 1703.
[Abstract] [Full Text] [PDF]

Home page
 NeurologyHome page
N. Scarmeas, G. M. Hadjigeorgiou, A. Papadimitriou, B. Dubois, M. Sarazin, J. Brandt, M. Albert, K. Marder, K. Bell, L. S. Honig, et al.
Motor signs during the course of Alzheimer disease
Neurology, September 28, 2004; 63(6): 975 - 982.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurol. Neurosurg. PsychiatryHome page
S Della Sala, H Spinnler, and A Venneri
Walking difficulties in patients with Alzheimer's disease might originate from gait apraxia
J. Neurol. Neurosurg. Psychiatry, February 1, 2004; 75(2): 196 - 201.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurol. Neurosurg. PsychiatryHome page
G Owen and G P Mulley
The palmomental reflex: a useful clinical sign?
J. Neurol. Neurosurg. Psychiatry, August 1, 2002; 73(2): 113 - 115.
[Abstract] [Full Text] [PDF]

Home page
 Arch NeurolHome page
R. S. Wilson, D. A. Bennett, D. W. Gilley, L. A. Beckett, J. A. Schneider, and D. A. Evans
Progression of Parkinsonism and Loss of Cognitive Function in Alzheimer Disease
Arch Neurol, June 1, 2000; 57(6): 855 - 860.
[Abstract] [Full Text] [PDF]

Home page
 NeurologyHome page
R. S. Wilson, D. A. Bennett, D. W. Gilley, L. A. Beckett, J. A. Schneider, and D. A. Evans
Progression of parkinsonian signs in Alzheimer's disease
Neurology, March 28, 2000; 54(6): 1284 - 1289.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurol. Neurosurg. PsychiatryHome page
R. RAO
Frontal release signs in older people with peripheral vascular disease
J. Neurol. Neurosurg. Psychiatry, January 1, 2000; 68(1): 105 - 106.
[Full Text]

Home page
 J Geriatr Psychiatry NeurolHome page
D. P. Holschneider and A. F. Leuchter
Clinical Neurophysiology Using Electroencephalography in Geriatric Psychiatry: Neurobiologic Implications and Clinical Utility
J Geriatr Psychiatry Neurol, October 1, 1999; 12(3): 150 - 164.
[Abstract] [PDF]

Home page
 J. Neuropsychiatry Clin. Neurosi.Home page
R. D. Sanders and M. S. Keshavan
The Neurologic Examination in Adult Psychiatry: From Soft Signs to Hard Science
J Neuropsychiatry Clin Neurosci, November 1, 1998; 10(4): 395 - 404.
[Abstract] [Full Text]

Home page
 Clin RehabilHome page
V. Pomeroy
Immobility and severe dementia: when is physiotherapy treatment appropriate?
Clinical Rehabilitation, August 1, 1994; 8(3): 226 - 232.
[Abstract] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.