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© 1991 Oxford University Press

research-article

A Comparison of Single-dose versus Conventional-dose Antibiotic Treatment of Bacteriuria in Elderly Women

P. G. FLANAGAN*, P. J. ROONEY, E. A. DAVIES and R. W. STOUT

Department of Geriatric medicine, The Queen's University of Belfast
Dpartment of Bacteriology, Belfast City Hospital

The efficacy of single-dose antibiotic therapy for the treatment of bacteriuria in a group of non-catheterized elderly women was compared with that of conventional 7–10 day courses of antibiotic therapy. Thirty-one women received single-dose treatment and 22 conventional-dose treatment. The cure rates at 1 and 6 weeks for the single-dose treatments were 52% and 38%respectively, and the cure rates for the conventional-dose treatments at 1 and 6 weeks were 59% and 52%, respectively. It is concluded that there may be a place for the use of single-dose antibiotic therapy for the treatment of selected elderly women with bacteriuria, but larger studies are needed.

Received August 24, 1990; Revision received August 24, 1990.
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