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© 1993 Oxford University Press

research-article

Prevalence and Change of Cardiovascular Risk Factors among Men born 1900–19: The Finnish Cohorts of the Seven Countries Study

AULIKKI NISSINEN, MARKKU TERVAHAUTA, JUHA PEKKANEN, PAULA KIVINEN, JARI STENGÅRD, ESKO KAARSALO, SIRKKA-LIISA KIVELÄ, SARI VÄISÄNEN, JUKKA T. SALONEN and JAAKKO TUOMILEHTO

Department of Community Health and General Practice, University of Kuopio PO Box 1627, SF-70211 Kuopio, Finland
Department of Environmental Hygiene and Toxicology, National Public Health Institute Kuopio
Division of Epidemiology, National Public Health Institute Helsinki
Loimaa Regional Hospital Loimaa
Department of Public Health and General Practice, University of Oulu
Kuopio Research Institute of Exercise Medicine Kuopio

In a 30-year follow-up survey of the Finnish cohorts of the Seven Countries Study in 1989, 470 men aged 70–89 years were examined in two rural areas of Finland, in the East and in the West. Life-style-related coronary heart disease risk factors were at high levels in both groups, but the difference between areas found in the same cohort in middle age had mostly disappeared or partially reversed.

Mean levels of systolic/diastolic blood pressure, body mass index, fasting blood glucose, blood glucose after 2-hour oral glucose tolerance test, and plasma fibrinogen were higher in the West than in the East (p<0.05), but serum thiocyanate which reflects smoking habits was higher in the East (p<0.001).

No significant differences between areas were found in mean levels of serum total cholesterol, LDL-cholesterol, HDL-cholesterol, triglycerides, apolipoprotein A-I, apolipoprotein B, lipoprotein (a), plasma coagulation factor VIIc, and prevalence of current smoking.

Received January 21, 1993;
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