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© 1995 Oxford University Press

research-article

Factors associated with Healing Leg Ulceration with High Compression

P.J. FRANKS1,*, CHRISTINE J. MOFFATT, MARJORIE CONNOLLY, NICK BOSANQUET, MARGARET I. OLDROYD, ROGER M. GREENHALGH and CHARLES N. MCCOLLUM

1Department of Surgery, Charing Cross Hospital Fulham Palace Road, London W6 8RF
Health Policy Unit, St Mary's Medical School, Lisson Grove Health Centre Gateforth Street, London NW8 8EG
University Hospital of South Manchester Nell Lane, West Didsbury, Manchester M20 8LR

* Dr P. J. Franks at the Centre for Research and Implementation of Clinical Practice, Riverside Community Healthcare Trust, 5–7 Parsons Green, London SW6 4UL

To investigate factors relevant to the healing of leg ulceration by high compression, patients were interviewed using a standard questionnaire prior to treatment with a four-layer bandage high-compression system in six community ulcer clinics. We explored the relation of size, ulcer duration and medical history to healing.

Cumulative healing rates were high using this method, being 69% after 12 weeks and 83% after 24 weeks. Twelve-week healing rates varied slightly between clinics, ranging from 62% to 83%. Univariate analysis of the total group showed that male sex (RR = 0.77, p = 0.023), poor limb joint mobility (RR = 0.39, p < 0.001), poor general mobility (RR = 0.49, p = 0.015), treatment at home (RR = 0.52, p < 0.001), ulcer size >10 cm2 (RR = 0.37, p < 0.001), history of deep vein thrombosis (RR = 0.67, p = 0.016) and ulcer duration >6 months (RR = 0.35, p < 0.001) were significantly inversely associated with healing. Ulcer size, duration, limb joint mobility and general mobility were significant independent factors in multivariate analysis.

Revision received January 17, 1995.
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