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© 1996 Oxford University Press

research-article

Myasthenia Gravis and Elderly People

F. SCHON1, M. DRAYSON2 and R. A. THOMPSON2

1Department of Neurology, Atkinson Morley's Hospital Copse Hill, Wimbledon London SW20 0NE
2Department of Immunology, Birmingham Hartlands Hospital Bordersley Green East Birmingham BG5 SS

Myasthenia gravis is probably commoner than previously suspected, the annual incidence being nearer 9–10/ million than earlier figures of 2–4/million. The current study found an annual incidence in Croydon of 9.1 per million (95% confidence limits 5.7–13.8 per million). Of the 22 patients (59%) seen in Croydon with newly diagnosed myasthenia gravis during the past 7 years, 13 were aged over 60. In a separate study of the age distribution of positive acetylcholine receptor antibody assays, 51% were 60 years or above in 1991, and 64% in 1994. The peak age in both sexes was 70–80, and numbers were greatest in men aged 60–80.

Revision received June 7, 1995.
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