Skip Navigation

This Article
Right arrow FREE Full Text (PDF) Freely available
Right arrow E-letters: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (2)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Ruse, C. E.
Right arrow Articles by Parker, S. G.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Ruse, C. E.
Right arrow Articles by Parker, S. G.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Age and Ageing 2001; 30: 449-454
© 2001, British Geriatrics Society

Reviews

Molecular genetics and age-related disease

Charlotte E. Ruse and Stuart G. Parker1,

Departments of Medicine for the Elderly and Respiratory Medicine, University of Leicester, Glenfield Hospital, Leicester, UK
1 Sheffield Institute for Studies on Ageing, University of Sheffield, Barnsley District General Hospital, Gawber Road, Barnsley S75 2EP, UK

Maintenance and repair processes are crucial to the pathogenesis of ageing and late-onset disease. Thus, there is increasing recognition of the importance of genetic factors in the development of late-onset conditions such as stroke, Parkinson's disease and osteoporosis, and accumulating evidence for a genetic component in the development of chronic obstructive pulmonary disease. We review the approaches and problems in the genetic investigation of complex disorders in old age, taking chronic obstructive pulmonary disease as an example.

Keywords: ageing, chronic obstructive pulmonary disease, molecular genetics


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Chronic Respiratory DiseaseHome page
C E Ruse and S G Parker
Genetics and the Dutch Hypothesis
Chronic Respiratory Disease, April 1, 2004; 1(2): 105 - 113.
[Abstract] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.