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Age and Ageing 2003; 32: 551-552
© 2003, British Geriatrics Society

Case Report

Montelukast-associated Churg–Strauss syndrome

Atef B. Michael1 and David Murphy2

1 Birmingham Heartlands Hospital, Bordsley Green, Birmingham B9 5SS, UK
2 St Mary’s Hospital, Newport, Isle of Wight PO30 5TG, UK

Address correspondence to: A.B. Michael. E-mail: abimichael{at}ukonline.co.uk

A 68-year-old asthmatic presented markedly unwell with arthralgia, mononeuritis multiplex, peripheral neuropathy, and eosinophilia. His past medical history included perennial rhinitis, and nasal polyps. Three months prior to admission his prednisolone was stopped and Montelukast was started. The diagnosis of Montelukast-associated Churg–Strauss syndrome was made. The drug was stopped and steroids started with general improvement and reduction of eosinophilia; however, the neurological deficit persisted.

Keywords: Churg–Strauss syndrome, Montelukast, leukotriene receptor antagonists

Received August 22, 2002; Revision received January 16, 2003. accepted in revised form January 16, 2003.


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