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Age and Ageing 2005 34(5):522-524; doi:10.1093/ageing/afi130
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© The Author 2005. Published by Oxford University Press on behalf of the British Geriatrics Society. All rights reserved. For Permissions, please email: journals.permissions@oupjournals.org

Case Report

Non-fatal haemophagocytic syndrome in an elderly patient

Roy L. Soiza1, Sharmistha Ghosh2, J. Kenneth McAlpine1 and Mark A. Vickers1

1 Department of Medicine for the Elderly, Woodend Hospital, Aberdeen AB15 6LS, UK
2 School of Medicine, University of Aberdeen, Aberdeen AB24 3FX, UK

Address correspondence to: R. L. Soiza. Email: roysoiza{at}doctors.org.uk

A frail 78-year-old man presented with lethargy, fever, splenomegaly and pancytopenia. Bone marrow aspirate showed marked haemophagocytosis. A diagnosis of haemophagocytic syndrome secondary to diffuse splenic large B-cell lymphoma was eventually made. Treatment with laparascopic splenectomy was successful. Secondary haemophagocytic syndrome is a rare complication of many common conditions, and is fatal if untreated. A brief literature review is included.

Keywords: haemophagocytosis, haemophagocytic syndrome, lymphoma, elderly

Received November 29, 2004; accepted in revised form May 12, 2005.


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