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Age and Ageing Advance Access originally published online on May 30, 2007
Age and Ageing 2007 36(4):400-406; doi:10.1093/ageing/afm059
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Copyright © The Author 2007. Published by Oxford University Press on behalf of the British Geriatrics Society.

Major depression among medically ill elders contributes to sustained poor mental health in their informal caregivers

Jane McCusker1,, Eric Latimer2, Martin Cole3, Antonio Ciampi4 and Maida Sewitch5

1 Department of Clinical Epidemiology and Community Studies, St. Mary's Hospital and Department of Epidemiology and Biostatistics, McGill University, Canada
2 Douglas Hospital Research Centre, and Department of Psychiatry, McGill University, Canada
3 Department of Psychiatry, St. Mary's Hospital and Department of Psychiatry, McGill University, Canada
4 Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Canada
5 Department of Medicine, McGill University, Canada

Address correspondence to: Jane McCusker. Tel: (514) 345-3511 ext. 5060; Fax: (514) 734-2652. Email: jane.mccusker{at}mcgill.ca

Background: no longitudinal studies have addressed the effect of late life depression on the physical and mental health status of their informal caregivers.

Objective: to examine whether a diagnosis of depression in older medical inpatients is associated with the physical and mental health status of their informal caregivers after 6 months, independent of the physical health of the care recipient.

Design: longitudinal observational study with 6-month follow-up.

Setting: two Montreal acute-care hospitals.

Subjects: a sample of 97 cognitively intact medical inpatients aged 65 and over and their informal caregivers, with oversampling of patients with a diagnosis of major or minor depression.

Methods: patient data included depression (current diagnosis, duration of current diagnosis, severity of symptoms, and history of depression), physical health (severity of illness, comorbidity, premorbid disability), and cognitive impairment. Caregiver data included relationship to patient, co-residence, and the physical and mental health status subscales of the SF-36. Multivariate linear regression analyses were conducted to determine the relationship between patient depression and caregiver 6 month SF-36 physical and mental scores, adjusting for baseline values, patient comorbidity, disability, and other patient and caregiver variables.

Results: patient characteristics included: mean age 79.3, 62% female, 46% major depression, 18% minor depression, 36% no depression. Caregiver characteristics included: 73% female, 35% co-resident spouse, 15% other co-resident relation, 50% not residing with the patient. Results of the multivariate analyses showed that in comparison with caregivers of patients without a current diagnosis f depressio, caregivers of those with major depression had a lower mental health score at follow-up (–9.54, 95% CI –16.66, –2.43), even though their physical health was slightly better (5.42 95% CI 0.04, 10.81).

Conclusions: a diagnosis of major depression in older medical inpatients is independently associated with poor mental health in their informal caregivers 6 months later.

Keywords: aged, depression, informal caregivers, mental health, longitudinal study, elderly

Received 8 August 2006; accepted in revised form 27 March 2007.


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