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Age and Ageing 2008 37(2):173-178; doi:10.1093/ageing/afm161
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Copyright © The Author 2008. Published by Oxford University Press on behalf of the British Geriatrics Society.

Anaemia impedes functional mobility after hip fracture surgery

Nicolai B. Foss1,2,, Morten Tange Kristensen3 and Henrik Kehlet4

1 Department of Anaesthesia, Hvidovre University Hospital, Hvidovre, Denmark
2 Department of Orthopaedic Surgery, Hvidovre University Hospital, Hvidovre, Denmark
3 Department of Physiotherapy, Hvidovre University Hospital, Hvidovre, Denmark
4 Department of Surgical Pathophysiology, Rigshospitalet, Copenhagen, Denmark

Address correspondence to: Nicolai B. Foss. Email: nbf{at}comxnet.dk

Background: the impact of anaemia on the outcome after a hip fracture surgery is controversial, but anaemia can potentially decrease the physical performance and thereby impede post-operative rehabilitation. We therefore conducted a prospective study to establish whether anaemia affected functional mobility in the early post-operative phase after a hip fracture surgery.

Patients and Methods: four hundred and eighty seven consecutive hip fracture patients, treated according to a well-defined multimodal rehabilitation programme with a uniform, liberal transfusion threshold, were studied. Hb was measured on each of the first three post-operative days, and anaemia defined as Hb <100 g/l. Functional mobility was measured with the Cumulated Ambulation Score (CAS).

Results: the results were obtained from 170, 132 and 116 patients who were found anaemic on the first, second and third post-operative day, respectively. A significant association between anaemia and the ability to walk independently before the correction of anaemia was present on each of the 3 days separately (P<0.05). A significant correlation was also found on each day between the functional score and the Hb level. A multivariate analysis integrating the type of surgery, medical complications and prefracture function showed that anaemia at the time of the physiotherapy session was an independent risk factor for not being able to walk on the third post-operative day [OR 0.41 (0.14–0.73) P = 0.002].

Conclusion: anaemia impedes functional mobility in the early post-operative phase after a hip fracture surgery and is an independent risk factor for patients not being able to walk post-operatively. The potential for a liberal transfusion policy to improve the rehabilitation potential in hip fracture patients with anaemia should be investigated.

Keywords: hip fracture, anaemia, rehabilitation, elderly

Received 3 June 2007; accepted in revised form 31 August 2007.


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