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Age and Ageing Advance Access originally published online on March 9, 2009
Age and Ageing 2009 38(4):483-484; doi:10.1093/ageing/afp026
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© The Author 2009. Published by Oxford University Press on behalf of the British Geriatrics Society. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Case Report

The right scan at the right time: reversible posterior leukoencephalopathy syndrome mimicking bilateral occipital lobe infarcts

Sameer Limaye and Jonathan Cooper

Leeds General Infirmary, Leeds Teaching Hospitals NHS Trust, Great George Street, Leeds, LS1 3EX, UK

Address correspondence to: S. Limaye. Tel: (+44) 7811400741; Fax: (+44) 113 3926557. Email: samlimaye{at}hotmail.com

Abstract

Reversible Posterior Leukoencephalopathy Syndrome (RPLS) is a relatively recently characterised neurological syndrome, first described by Hinchey et al in 1996, with neuroimaging findings of reversible vasogenic subcortical oedema. The clinical presentation can vary, is often non-specific but can include headache, global encephalopathy, seizures and visual disturbances. In this article we present such a case in a 79 year old woman, followed by a discussion of the typical presentations, associations, pathomechanisms and neuroimaging findings.

Keywords: RPLS, elderly, PRES, stroke

Received 7 October 2008; accepted in revised form 30 January 2009.


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