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© 1977 Oxford University Press

research-article

HYPERCALCAEMIA IN ELDERLY HOSPITAL IN-PATIENTS: VALUE OF DISCRIMINANT ANALYSIS IN DIFFERENTIAL DIAGNOSIS

P. S. GRERO* and H. M. HODKINSON

Northwick Park Hospital Harrow, Middlesex, HA1 3UJ

Plasma calcium was measured routinely as a part of profile sreening of patients admitted to a geriatric department.

Pathological hypercalcaemia was found in 1.33% of those screened, the causes being b one metastases (29%), hyperparathyroidism (21%), bronchial carcinoma without bone metastasis (18.5%), lymphosarcoma without bone metastasis (8%) and multiple myeloma (2.5%). There remained a further group of patients with hypercalcaemia and renal failure (21%) in whom diagnosis wan often obscure.

Where renal function was normal, discriminant analysis showed that the four main diagnostic groups were bidemically distinguishable. Discriminant analysis thus seems likely to be of practical value in the differentil diagnosis of hypercalcaemia in elderly patients with normal renalfunction, but requires prospective validation.


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