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© 1978 Oxford University Press

research-article

HIGH-DOSE STEROID THERAPY OF INTRACRANIAL TUMOUR IN THE ELDERLY

K. GRAHAM and F. I. CAIRD

University Department of Geriatric Medicine, Southern General Hospital Glasgow G51 4TF

Correspondence to: Dr F. I. Caird

Twenty elderly patients with intracranial tumour were treated with high-dose steroids (beta- or dexamethasone 12–16 mg per day). Six of eight patients with primary intracranial malignancies and four of six with metastatic tumours showed a definite response of conscious level and/or neurological deficit. One of two patients with lymphoma responded but neither of two with meningioma. Six patients were able to return home. Two patients suffered serious, and three minor, side-effects attributable to steroid therapy, but this treatment has a definite place in the management of intracranial tumour in old age.


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