© 1980 Oxford University Press
research-article |
AGED MEN AND ISCHAEMIC HEART DISEASE: SERUM CHOLESTEROL AND TRIGLYCERIDE LEVELS
1Clinical Gerontology Unit, St Francis Hospital London, SE22 8DF
2Department of Biochemistry, University of Surrey
Requests for reprints should be addressed to B.L.
Fasting serum cholesterol and triglyceride levels, and lipoprotein electrophoretic patterns have been investigated in 42 men aged 6792 years (mean 79 years). Although all the cholesterol and the majority of the triglyceride levels were within the normal range for younger people, both were significantly greater (P< 0.001 and P<0.01 respectively) in old men who had a clinical history of ischaemic heart disease than in the aged controls, whereas, in patients with dysrhythmia-ischaemia the cholesterol levels were raised (P < 0.05) but not the triglycerides. An abnormality of lipoprotein profile was observed in 58% of patients with ischaemic heart disease; 7% of the controls; and 20% of patients having myocardial ischaemia associated with supraventricular dysrhythmia.