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© 1995 Oxford University Press

research-article

Risk Factors for Leg Ulcer Recurrence: A Randomized Trial of Two Types of Compression Stocking

PETER J. FRANKS1, MARGARET I. OLDROYD2, DEBORAH DICKSON2, ELIZABETH J. SHARP2 and CHRISTINE J. MOFFATT1

1Centre fur Research and Implementation of Clinical Practice, at the Royal Masonic Hospital, Ravenscourt Park London W6 OTN
2Department of Surgery, Charing Cross and Westminster Medical School St Dunstan's Road, London W6 8RF

Patients with recently healed leg ulceration were entered into a study of leg ulcer recurrence. In all, 188 patients [69% women, mean age = 72 (SD = 12) years] were entered into the study, of whom 166 were considered suitable for ready-made stockings and were randomized to one of two class II below-knee compression stockings and followed for at least 18 months. The remaining patients required either made-to-measure stockings (5) or could not tolerate stockings owing to friable skin and were treated by other methods (17).

Overall cumulative recurrence rate was 26% after 1 year and 31% at 18 months. Independent risk factors for recurrence were previous ulcer size >10 cm 2 (RR = 2.13, p = 0.009), history of deep vein thrombosis (RR = 2.34, p = 0.021) and unsuitability for stockings (RR = 2.52, p = 0.013). The randomized groups had similar cumulative 18-month recurrence rate (24% vs. 32%, p = 0.353). Of the 166 patients randomized to stockings, 25 (15%) could not put their stockings on at all and 43 (26%) were only able to put them on with great difficulty. The two stocking types differed significantly in this regard when analysed for trend.

Revision received April 24, 1995.
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