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Age and Ageing 2005 34(6):648-649; doi:10.1093/ageing/afi161
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© The Author 2005. Published by Oxford University Press on behalf of the British Geriatrics Society. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Collapse in a 79-year-old: a rare case of amyloid tumour of the pelvis

Sally A. Shiels1, Syed I. Hasan2 and Adam Darowski2

1 Osler House, John Radcliffe Hospital, Headington, Oxford OX3 9DU, UK
2 Department of Geratology, Radcliffe Infirmary, Oxford OX2 6HE, UK

Address correspondence to: S. A. Shiels. Email: sallyanne.shiels{at}green.ox.ac.uk

A 79-year-old man presented to accident and emergency with collapse, unable to bear weight on his left leg. Computed tomography revealed a large isolated lesion (28 x 12 x 8 cm) extending from the pelvis into the abdomen, affecting the left lumbrosacral nerves. Further investigations showed that the mass contained amyloid protein. With no evidence of systemic amyloidosis or malignancy a diagnosis of amyloidoma/amyloid tumour was made. This is the largest amyloid tumour reported in the literature to date. There is limited but conflicting evidence regarding the pathophysiology, management and prognosis of amyloidoma. Clearly amyloidomas are rare, but patients can present acutely and may have a poor prognosis, especially when the tumour is of considerable size.

Keywords: amyloid tumour, amyloidoma, plasmacytoma, elderly

Received January 4, 2005; accepted in revised form June 29, 2005.


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