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© 1978 Oxford University Press

research-article

ULTRA-VIOLET IRRADIATION AND 25-HYDROXY-VITAMIN D LEVELS IN SICK OLD PEOPLE

A. P. SNELL1, W. J. MACLENNAN2 and JUDITH C. HAMILTON3

1Department of Geriatric Medicine, Southampton General Hospital Tremona Road, Southampton SO9 4XY
2Department of Geriatric Medicine, University of Southampton
3Department of Biochemistry, University of Southampton

Twelve elderly patients in a rehabilitation ward were given a four-week course of ultra-violet irradiation from a Vitalux lamp. They were compared with 12 controls selected from the same ward. Treatment produced a significant elevation in plasma 25-hydroxy-vitamin D (25OHD) by the end of the second week and concentrations continued to rise over the four-week period. Subjects showing the greatest response were those starting with the lowest levels of plasma 25OHD. The findings suggest that ultra-violet irradiation is an effective means of treating vitamin D deficiency in old age and that patients with the greatest degree of deficiency show the greatest response.


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