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Age and Ageing Advance Access published online on January 11, 2006
Age and Ageing, doi:10.1093/ageing/afj021
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© The Author 2006. Published by Oxford University Press on behalf of the British Geriatrics Society. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org
Received March 30, 2005
Accepted November 4, 2005

Case Report

Acute Epstein-Barr virus infection in two elderly individuals

Spyros P. Dourakis 1 *, Alexandra Alexopoulou 1, Nikolas Stamoulis 1, Apostolos Foutris 1, Helen Pandelidaki 1, and Athanasios J. Archimandritis 1

1 Second Department of Medicine, University of Athens Medical School, Hippokration General Hospital, 114 Vas. Sophias St, 11523 Athens, Greece

* To whom correspondence should be addressed.
Spyros P. Dourakis, E-mail: spiros{at}ath.forthnet.gr


  Abstract

Most individuals acquire Epstein-Barr virus (EBV) infection in young age. Because of uncommon presentation and misdiagnosis, clinical manifestations are less well described in older age. We present two cases of elderly patients with predominant symptoms attributed to cold agglutinin haemolytic anaemia due to acute EBV infection without fever, lymphadenopathy, pharyngitis or splenomegaly. We conclude that misleading clinical manifestations are frequent in older individuals and may lead to inappropriate diagnostic invasive procedures.

Keywords: acute EBV infection, elderly individuals, cold agglutinin haemolytic anaemia, elderly.
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