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Age and Ageing Advance Access published online on April 2, 2008
Age and Ageing, doi:10.1093/ageing/afn063
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Copyright © The Author 2008. Published by Oxford University Press on behalf of the British Geriatrics Society.

Case Report

Ataxia caused by amiodarone in older people

J. V. Hindle, Amin Ibrahim and Radhakrishnan Ramaraj

Department of Care of the Elderly, Llandudno Hospital, North West Wales NHS Trust, Llandudno, Conwy, LL30 1LB, UK

Address correspondence to: J. V. Hindle. Tel: 01492 862366; Fax: 01492 876973. Email: john.hindle{at}nww-tr.wales.nhs.uk

Abstract

Amiodarone is recommended for the cardioversion of atrial fibrillation and prevention of paroxysmal atrial fibrillation in patients with structural heart disease, coronary artery disease or left ventricular dysfunction. It has well-recognised side-effects on the skin, lungs, liver, thyroid and eyes. Neurological side-effects, including ataxia and neuropathy, also occur, and may be more prevalent in older patients. These side-effects are reversible after cessation of amiodarone. Monitoring of amiodarone therapy should include assessment of the central and peripheral nervous system especially in older patients.

Keywords: amiodarone, ataxia, side-effects, neuropathy, elderly

Received 25 May 2007; accepted in revised form 30 November 2007.


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